Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells

BACKGROUND & AIMS: Pancreatic acinar cells have an expanded apical endosomal system, the physiologic and pathophysiologic significance of which is still emerging. Phosphatidylinositol-3,5-bisphosphate [PI(3,5)P(2)] is an essential phospholipid generated by phosphatidylinositol 3-phosphate 5-kina...

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Dades bibliogràfiques
Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Messenger, Scott W., Thomas, Diana D.H., Cooley, Michelle M., Jones, Elaina K., Falkowski, Michelle A., August, Benjamin K., Fernandez, Luis A., Gorelick, Fred S., Groblewski, Guy E.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657148/
https://ncbi.nlm.nih.gov/pubmed/26618189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.08.002
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