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Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells
BACKGROUND & AIMS: Pancreatic acinar cells have an expanded apical endosomal system, the physiologic and pathophysiologic significance of which is still emerging. Phosphatidylinositol-3,5-bisphosphate [PI(3,5)P(2)] is an essential phospholipid generated by phosphatidylinositol 3-phosphate 5-kina...
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| Veröffentlicht in: | Cell Mol Gastroenterol Hepatol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657148/ https://ncbi.nlm.nih.gov/pubmed/26618189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.08.002 |
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