Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells

Zymogen granule (ZG) formation in acinar cells involves zymogen cargo sorting from trans-Golgi into immature secretory granules (ISGs). ISG maturation progresses by removal of lysosomal membrane and select content proteins, which enter endosomal intermediates prior to their apical exocytosis. Consti...

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Bibliografiske detaljer
Main Authors: Messenger, Scott W., Thomas, Diana D. H., Falkowski, Michelle A., Byrne, Jennifer A., Gorelick, Fred S., Groblewski, Guy E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Pancreas
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761242/
https://ncbi.nlm.nih.gov/pubmed/23868405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00143.2013
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