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p53 dynamics upon response element recognition explored by molecular simulations
p53 is a representative transcription factor that activates multiple target genes. To realize stimulus-dependent specificities, p53 has to recognize targets with structural variety, of which molecular mechanisms are largely unknown. Here, we conducted a series of long-time scale (totally more than 1...
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| Publicado no: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656996/ https://ncbi.nlm.nih.gov/pubmed/26596470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17107 |
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