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Multiscale Ensemble Modeling of Intrinsically Disordered Proteins: p53 N-Terminal Domain

Intrinsically disordered proteins (IDPs) are ubiquitous and play key roles in transcriptional regulations and other cellular processes. To characterize diverse structural ensembles of IDPs, combinations of NMR and computational modeling showed some promise, but they need further improvements. Here,...

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Bibliographic Details
Main Authors: Terakawa, Tsuyoshi, Takada, Shoji
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177054/
https://ncbi.nlm.nih.gov/pubmed/21943426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.003
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