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Molecular Dynamics Simulations of p53 DNA-Binding Domain

We have studied room-temperature structural and dynamic properties of the p53 DNA-binding domain in both DNA-bound and DNA-free states. A cumulative 55ns of explicit solvent molecular dynamics simulations with the Particle Mesh Ewald treatment of electrostatics were performed. It is found that the m...

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Detalhes bibliográficos
Main Authors: Lu, Qiang, Tan, Yu-Hong, Luo, Ray
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522240/
https://ncbi.nlm.nih.gov/pubmed/17824689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp0742261
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