Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli.
We have designed and utilized a bacterial complementation system to identify and characterize mammalian DNA polymerase beta mutants. In this complementation system, wild-type rat DNA polymerase beta replaces both the replicative and repair functions of DNA polymerase I in the Escherichia coli recA71...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4626 |
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