Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli.

We have designed and utilized a bacterial complementation system to identify and characterize mammalian DNA polymerase beta mutants. In this complementation system, wild-type rat DNA polymerase beta replaces both the replicative and repair functions of DNA polymerase I in the Escherichia coli recA71...

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Bibliografiska uppgifter
Huvudupphovsmän: Sweasy, J B, Loeb, L A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC46565/
https://ncbi.nlm.nih.gov/pubmed/8506308
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