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Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy

Colorectal cancer is commonly treated with 5-fluorouracil and 5-formyltetrahydrofolate (leucovorin). Metabolic action of leucovorin requires several enzymatic steps that are dependent on expression of corresponding coding genes. To identify folate pathway genes with possible impact on leucovorin met...

詳細記述

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書誌詳細
出版年:Mol Med
主要な著者: Odin, Elisabeth, Sondén, Arvid, Gustavsson, Bengt, Carlsson, Göran, Wettergren, Yvonne
フォーマット: Artigo
言語:Inglês
出版事項: The Feinstein Institute Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656203/
https://ncbi.nlm.nih.gov/pubmed/26193446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00192
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