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Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy

Colorectal cancer is commonly treated with 5-fluorouracil and 5-formyltetrahydrofolate (leucovorin). Metabolic action of leucovorin requires several enzymatic steps that are dependent on expression of corresponding coding genes. To identify folate pathway genes with possible impact on leucovorin met...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Odin, Elisabeth, Sondén, Arvid, Gustavsson, Bengt, Carlsson, Göran, Wettergren, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656203/
https://ncbi.nlm.nih.gov/pubmed/26193446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00192
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