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Relationship between folate concentration and expression of folate-associated genes in tissue and plasma after intraoperative administration of leucovorin in patients with colorectal cancer

PURPOSE: The aim of study was to investigate the relationship between folate concentration and expression of folate-associated genes in tumour, mucosa and plasma of patients with colorectal cancer, after intraoperative administration of bolus leucovorin (LV). METHODS: Eighty patients were randomized...

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Détails bibliographiques
Publié dans:Cancer Chemother Pharmacol
Auteurs principaux: Taflin, Helena, Odin, Elisabeth, Derwinger, Kristoffer, Carlsson, Göran, Gustavsson, Bengt, Wettergren, Yvonne
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267663/
https://ncbi.nlm.nih.gov/pubmed/30269276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-018-3690-9
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