Dysregulated metabolism contributes to oncogenesis

Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth, cancer cells undergo a complex metabolic rearrangement characterized by changes in metabolic pathways involved in energy production and biosynthetic processes. The relevance of the metabolic transfo...

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Udgivet i:Semin Cancer Biol
Main Authors: Hirschey, Matthew D., DeBerardinis, Ralph J., Diehl, Anna Mae E., Drew, Janice E., Frezza, Christian, Green, Michelle F., Jones, Lee W., Ko, Young H., Le, Anne, Lea, Michael A., Locasale, Jason W., Longo, Valter D., Lyssiotis, Costas A., McDonnell, Eoin, Mehrmohamadi, Mahya, Michelotti, Gregory, Muralidhar, Vinayak, Murphy, Michael P., Pedersen, Peter L., Poore, Brad, Raffaghello, Lizzia, Rathmell, Jeffrey C., Sivanand, Sharanya, Vander Heiden, Matthew G., Wellen, Kathryn E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656121/
https://ncbi.nlm.nih.gov/pubmed/26454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.10.002
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