Dysregulated metabolism contributes to oncogenesis

Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth, cancer cells undergo a complex metabolic rearrangement characterized by changes in metabolic pathways involved in energy production and biosynthetic processes. The relevance of the metabolic transfo...

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Veröffentlicht in:Semin Cancer Biol
Hauptverfasser: Hirschey, Matthew D., DeBerardinis, Ralph J., Diehl, Anna Mae E., Drew, Janice E., Frezza, Christian, Green, Michelle F., Jones, Lee W., Ko, Young H., Le, Anne, Lea, Michael A., Locasale, Jason W., Longo, Valter D., Lyssiotis, Costas A., McDonnell, Eoin, Mehrmohamadi, Mahya, Michelotti, Gregory, Muralidhar, Vinayak, Murphy, Michael P., Pedersen, Peter L., Poore, Brad, Raffaghello, Lizzia, Rathmell, Jeffrey C., Sivanand, Sharanya, Vander Heiden, Matthew G., Wellen, Kathryn E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656121/
https://ncbi.nlm.nih.gov/pubmed/26454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.10.002
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