Dysregulated metabolism contributes to oncogenesis

Cancer is a disease characterized by unrestrained cellular proliferation. In order to sustain growth, cancer cells undergo a complex metabolic rearrangement characterized by changes in metabolic pathways involved in energy production and biosynthetic processes. The relevance of the metabolic transfo...

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Vydáno v:Semin Cancer Biol
Hlavní autoři: Hirschey, Matthew D., DeBerardinis, Ralph J., Diehl, Anna Mae E., Drew, Janice E., Frezza, Christian, Green, Michelle F., Jones, Lee W., Ko, Young H., Le, Anne, Lea, Michael A., Locasale, Jason W., Longo, Valter D., Lyssiotis, Costas A., McDonnell, Eoin, Mehrmohamadi, Mahya, Michelotti, Gregory, Muralidhar, Vinayak, Murphy, Michael P., Pedersen, Peter L., Poore, Brad, Raffaghello, Lizzia, Rathmell, Jeffrey C., Sivanand, Sharanya, Vander Heiden, Matthew G., Wellen, Kathryn E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656121/
https://ncbi.nlm.nih.gov/pubmed/26454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.10.002
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