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Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus

Human islet amyloid polypeptide (h-IAPP) is a peptide hormone that is synthesized and cosecreted with insulin from insulin-secreting pancreatic β-cells. Recently, h-IAPP was proposed to be the main component responsible for the cytotoxic pancreatic amyloid deposits in patients with type 2 diabetes m...

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Publicat a:Clin Interv Aging
Autors principals: Jeong, Hye Rin, An, Seong Soo A
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655906/
https://ncbi.nlm.nih.gov/pubmed/26604727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S95297
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