Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720

Effective therapeutic agents are lacking for the prevention and reversal of vascular leak, a frequent pathophysiologic result of inflammatory processes such as acute respiratory distress syndrome (ARDS) and sepsis. We previously demonstrated the potent barrier-enhancing effects of related compounds...

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Pubblicato in:Chem Phys Lipids
Autori principali: Camp, Sara M., Chiang, Eddie T., Sun, Chaode, Usatyuk, Peter V., Bittman, Robert, Natarajan, Viswanathan, Garcia, Joe G. N., Dudek, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655823/
https://ncbi.nlm.nih.gov/pubmed/26272033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2015.08.004
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