Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers

RATIONALE: Vascular permeability is a hallmark of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury pathobiology; however, the mechanisms underlying this vascular dysregulation remain unclear, thereby impairing the development of desperately needed effective therapeutics....

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Pubblicato in:Pulm Circ
Autori principali: Camp, Sara M., Marciniak, Alexander, Chiang, Eddie T., Garcia, Alexander N., Bittman, Robert, Polt, Robin, Perez, Ruth G., Dudek, Steven M., Garcia, Joe G. N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011338/
https://ncbi.nlm.nih.gov/pubmed/32095229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020905521
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