Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

BACKGROUND: The RTS,S/AS01 malaria vaccine targets the circumsporozoite protein, inducing antibodies associated with the prevention of Plasmodium falciparum infection. We assessed the association between anti-circumsporozoite antibody titres and the magnitude and duration of vaccine efficacy using d...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Lancet Infect Dis
المؤلفون الرئيسيون: White, Michael T, Verity, Robert, Griffin, Jamie T, Asante, Kwaku Poku, Owusu-Agyei, Seth, Greenwood, Brian, Drakeley, Chris, Gesase, Samwel, Lusingu, John, Ansong, Daniel, Adjei, Samuel, Agbenyega, Tsiri, Ogutu, Bernhards, Otieno, Lucas, Otieno, Walter, Agnandji, Selidji T, Lell, Bertrand, Kremsner, Peter, Hoffman, Irving, Martinson, Francis, Kamthunzu, Portia, Tinto, Halidou, Valea, Innocent, Sorgho, Hermann, Oneko, Martina, Otieno, Kephas, Hamel, Mary J, Salim, Nahya, Mtoro, Ali, Abdulla, Salim, Aide, Pedro, Sacarlal, Jahit, Aponte, John J, Njuguna, Patricia, Marsh, Kevin, Bejon, Philip, Riley, Eleanor M, Ghani, Azra C
التنسيق: Artigo
اللغة:Inglês
منشور في: Elsevier Science ;, The Lancet Pub. Group 2015
الموضوعات:
Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655306/
https://ncbi.nlm.nih.gov/pubmed/26342424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(15)00239-X
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