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Imbalanced PTEN and Phosphoinositide 3-kinase signaling impairs class switch recombination()
Class switch recombination (CSR) generates isotype-switched antibodies with distinct effector functions. B cells express phosphatase and tensin homolog (PTEN) and multiple isoforms of class IA phosphoinositide 3-kinase (PI3K) catalytic subunits, including p110α and p110δ, whose roles in CSR remain u...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655169/ https://ncbi.nlm.nih.gov/pubmed/26500350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501375 |
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