Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects

Antibody production and function represent an essential part of the immune response, particularly in fighting bacterial and viral infections. Multiple immunological phenotypes can result in dysregulation of the immune system humoral compartment, including class-switch recombination (CSR) defects ass...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Jhamnani, Rekha D., Nunes-Santos, Cristiane J., Bergerson, Jenna, Rosenzweig, Sergio D.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168630/
https://ncbi.nlm.nih.gov/pubmed/30319630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02172
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