A carregar...
TRAF2 deficiency in B cells impairs CD40-induced isotype-switching that can be rescued by restoring NF-κB1 activation
Effective humoral immunity requires class switch recombination (CSR) catalyzed by activation-induced deaminase (AID). In response to T cell-dependent (TD) antigens, CSR can be induced by CD40 signaling in B cells. Tumor necrosis factor receptor associated factors 2 and 3 (TRAF2/TRAF3) function as ad...
Na minha lista:
| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6246814/ https://ncbi.nlm.nih.gov/pubmed/30341187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800337 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|