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NF-κB2 mutation targets TRAF1 to induce lymphomagenesis

The NF-κB2 gene is recurrently mutated in human lymphoid malignancies. However, a causal relationship between NF-κB2 mutation and lymphomagenesis has not been established. It is also unclear how the mutation may lead to lymphoid malignancies. We report the generation of transgenic mice with targeted...

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Detalhes bibliográficos
Main Authors: Zhang, Baochun, Wang, Zhe, Li, Tai, Tsitsikov, Erdyni N., Ding, Han-Fei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924489/
https://ncbi.nlm.nih.gov/pubmed/17405906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-058446
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