Targeting NF-κB in Waldenstrom macroglobulinemia

The nuclear factor-κB (NF-κB) path-way has been implicated in tumor B-cell survival, growth, and resistance to therapy. Because tumor cells overcome single-agent antitumor activity, we hypothesized that combination of agents that target differentially NF-κB pathway will induce significant cytotoxici...

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Hlavní autoři: Leleu, Xavier, Eeckhoute, Jérôme, Jia, Xiaoying, Roccaro, Aldo M., Moreau, Anne-Sophie, Farag, Mena, Sacco, Antonio, Ngo, Hai T., Runnels, Judith, Melhem, Molly R., Burwick, Nicolas, Azab, Abdelkareem, Azab, Feda, Hunter, Zachary, Hatjiharissi, Evdoxia, Carrasco, Daniel R., Treon, Steven P., Witzig, Thomas E., Hideshima, Teru, Brown, Myles, Anderson, Kenneth C., Ghobrial, Irene M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384134/
https://ncbi.nlm.nih.gov/pubmed/18334673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115170
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