Targeting NF-κB in Waldenstrom macroglobulinemia

The nuclear factor-κB (NF-κB) path-way has been implicated in tumor B-cell survival, growth, and resistance to therapy. Because tumor cells overcome single-agent antitumor activity, we hypothesized that combination of agents that target differentially NF-κB pathway will induce significant cytotoxici...

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Bibliografiske detaljer
Main Authors: Leleu, Xavier, Eeckhoute, Jérôme, Jia, Xiaoying, Roccaro, Aldo M., Moreau, Anne-Sophie, Farag, Mena, Sacco, Antonio, Ngo, Hai T., Runnels, Judith, Melhem, Molly R., Burwick, Nicolas, Azab, Abdelkareem, Azab, Feda, Hunter, Zachary, Hatjiharissi, Evdoxia, Carrasco, Daniel R., Treon, Steven P., Witzig, Thomas E., Hideshima, Teru, Brown, Myles, Anderson, Kenneth C., Ghobrial, Irene M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2008
Fag:
Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384134/
https://ncbi.nlm.nih.gov/pubmed/18334673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115170
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