Targeting NF-κB in Waldenstrom macroglobulinemia

The nuclear factor-κB (NF-κB) path-way has been implicated in tumor B-cell survival, growth, and resistance to therapy. Because tumor cells overcome single-agent antitumor activity, we hypothesized that combination of agents that target differentially NF-κB pathway will induce significant cytotoxici...

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Autors principals: Leleu, Xavier, Eeckhoute, Jérôme, Jia, Xiaoying, Roccaro, Aldo M., Moreau, Anne-Sophie, Farag, Mena, Sacco, Antonio, Ngo, Hai T., Runnels, Judith, Melhem, Molly R., Burwick, Nicolas, Azab, Abdelkareem, Azab, Feda, Hunter, Zachary, Hatjiharissi, Evdoxia, Carrasco, Daniel R., Treon, Steven P., Witzig, Thomas E., Hideshima, Teru, Brown, Myles, Anderson, Kenneth C., Ghobrial, Irene M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2384134/
https://ncbi.nlm.nih.gov/pubmed/18334673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115170
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