A Novel Tandem Duplication Assay to Detect Minimal Residual Disease in FLT3/ITD AML

BACKGROUND: Internal tandem duplication (ITD) of the FLT3 gene is associated with poor prognosis in acute myeloid leukemia (AML) patients with a normal karyotype. The current standard PCR assay for FLT3/ITD detection is not sufficiently sensitive to monitor minimal residual disease (MRD). Clone-spec...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Diagn Ther
Main Authors: Lin, Ming-Tseh, Tseng, Li-Hui, Dudley, Jonathan C., Riel, Stacey, Tsai, Harrison, Zheng, Gang, Pratz, Keith W., Levis, Mark J., Gocke, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655128/
https://ncbi.nlm.nih.gov/pubmed/26446915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-015-0170-3
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker