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Optimal experimental designs for dose–response studies with continuous endpoints

In most areas of clinical and preclinical research, the required sample size determines the costs and effort for any project, and thus, optimizing sample size is of primary importance. An experimental design of dose–response studies is determined by the number and choice of dose levels as well as th...

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Dades bibliogràfiques
Publicat a:Arch Toxicol
Autors principals: Holland-Letz, Tim, Kopp-Schneider, Annette
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655015/
https://ncbi.nlm.nih.gov/pubmed/25155192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1335-2
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