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Optimal experimental designs for dose–response studies with continuous endpoints

In most areas of clinical and preclinical research, the required sample size determines the costs and effort for any project, and thus, optimizing sample size is of primary importance. An experimental design of dose–response studies is determined by the number and choice of dose levels as well as th...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Holland-Letz, Tim, Kopp-Schneider, Annette
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655015/
https://ncbi.nlm.nih.gov/pubmed/25155192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1335-2
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