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Optimal experimental designs for dose–response studies with continuous endpoints

In most areas of clinical and preclinical research, the required sample size determines the costs and effort for any project, and thus, optimizing sample size is of primary importance. An experimental design of dose–response studies is determined by the number and choice of dose levels as well as th...

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Библиографические подробности
Опубликовано в: :Arch Toxicol
Главные авторы: Holland-Letz, Tim, Kopp-Schneider, Annette
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655015/
https://ncbi.nlm.nih.gov/pubmed/25155192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-014-1335-2
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