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Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9
The E1 helicase from BPV and HPV16 interacts with Ubc9 to facilitate viral genome replication. We report that HPV11 E1 also interacts with Ubc9 in vitro and in the yeast two-hybrid system. Residues in E1 involved in oligomerization (353–435) were sufficient for binding to Ubc9 in vitro, but the orig...
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| Publicado en: | Virology |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4654619/ https://ncbi.nlm.nih.gov/pubmed/19836047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.09.020 |
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