載入...

Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects

BACKGROUND: TAK-438 (vonoprazan) is a potassium-competitive acid blocker that reversibly inhibits gastric H(+), K(+)-ATPase. AIM: To evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-438 in healthy Japanese and non-Japanese men. METHODS: In two Phase I, randomised, doub...

全面介紹

Na minha lista:
書目詳細資料
發表在:Aliment Pharmacol Ther
Main Authors: Jenkins, H, Sakurai, Y, Nishimura, A, Okamoto, H, Hibberd, M, Jenkins, R, Yoneyama, T, Ashida, K, Ogama, Y, Warrington, S
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654261/
https://ncbi.nlm.nih.gov/pubmed/25707624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.13121
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!