An anthrax toxin variant with an improved activity in tumor targeting

Anthrax lethal toxin (LT) is an A-B type toxin secreted by Bacillus anthracis, consisting of the cellular binding moiety, protective antigen (PA), and the catalytic moiety, lethal factor (LF). To target cells, PA binds to cell-surface receptors and is then proteolytically processed forming a LF-bind...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wein, Alexander N., Peters, Diane E., Valivullah, Zaheer, Hoover, Benjamin J., Tatineni, Aparna, Ma, Qian, Fattah, Rasem, Bugge, Thomas H., Leppla, Stephen H., Liu, Shihui
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653645/
https://ncbi.nlm.nih.gov/pubmed/26584669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16267
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires