Llwytho...

Comparative toxicity and efficacy of engineered anthrax lethal toxin variants with broad anti-tumor activities

We have previously designed and characterized versions of anthrax lethal toxin that are selectively cytotoxic in the tumor microenvironment and which display broad and potent anti-tumor activities in vivo. Here, we have performed the first direct comparison of the safety and efficacy of three engine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peters, Diane E., Hoover, Benjamin, Cloud, Loretta Grey, Liu, Shihui, Molinolo, Alfredo A., Leppla, Stephen H., Bugge, Thomas H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137396/
https://ncbi.nlm.nih.gov/pubmed/24971906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.06.010
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