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Comparative toxicity and efficacy of engineered anthrax lethal toxin variants with broad anti-tumor activities
We have previously designed and characterized versions of anthrax lethal toxin that are selectively cytotoxic in the tumor microenvironment and which display broad and potent anti-tumor activities in vivo. Here, we have performed the first direct comparison of the safety and efficacy of three engine...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137396/ https://ncbi.nlm.nih.gov/pubmed/24971906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.06.010 |
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