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A versatile transgenic allele for mouse overexpression studies
For the analysis of gene function in vivo, gene overexpression in the mouse provides an alternative to loss-of-function knock-out approaches and can help reveal phenotypes where compensatory mechanisms are at play. Furthermore, when multiple lines overexpressing a gene-of-interest at varying levels...
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| Publicado en: | Mamm Genome |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer US
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653235/ https://ncbi.nlm.nih.gov/pubmed/26369329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9602-y |
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