Mutation of N-linked glycosylation at Asn548 in CD133 decreases its ability to promote hepatoma cell growth

The membrane glycoprotein CD133 is a popular marker for cancer stem cells and contributes to cancer initiation and invasion in a number of tumor types. CD133 promotes tumorigenesis partly through an interaction between its phosphorylated Y828 residue and the PI3K regulatory subunit p85, and the inte...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Ying, Ren, Shifang, Xie, Liqi, Cui, Chunhong, Xing, Yang, Liu, Chanjuan, Cao, Benjin, Yang, Fan, Li, Yinan, Chen, Xiaoning, Wei, Yuanyan, Lu, Haojie, Jiang, Jianhai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653032/
https://ncbi.nlm.nih.gov/pubmed/26029999
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