ROS1 amplification mediates resistance to gefitinib in glioblastoma cells

Glioblastoma (GBM) is the most aggressive brain tumor in adults and remains incurable despite multimodal intensive treatment regimens. The majority of GBM tumors show a mutated or overexpressed EGFR, however, tumors treated with tyrosine kinase inhibitors (TKIs) will inevitably recur highlighting th...

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Spremljeno u:
Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Aljohani, Hashim, Koncar, Robert F., Zarzour, Ahmad, Park, Byung Sun, Lee, So Ha, Bahassi, El Mustapha
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653012/
https://ncbi.nlm.nih.gov/pubmed/25978031
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