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Krüppel‐like factor 4 promotes c‐Met amplification‐mediated gefitinib resistance in non‐small‐cell lung cancer

Gefitinib has been widely used in the first‐line treatment of advanced EGFR‐mutated non‐small‐cell lung cancer (NSCLC). However, many NSCLC patients will acquire resistance to gefitinib after 9‐14 months of treatment. This study revealed that Krüppel‐like factor 4 (KLF4) contributes to the formation...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Feng, Wei, Xie, Qianyi, Liu, Suo, Ji, Ying, Li, Chunyun, Wang, Chunle, Jin, Longyu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989843/
https://ncbi.nlm.nih.gov/pubmed/29624806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13601
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