Loading...
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
In human lung adenocarcinomas harboring EGFR mutations, a second-site point mutation that substitutes methionine for threonine at position 790 (T790M) is associated with approximately half of cases of acquired resistance to the EGFR kinase inhibitors, gefitinib and erlotinib. To identify other poten...
Na minha lista:
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
National Academy of Sciences
2007
|
Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409244/ https://ncbi.nlm.nih.gov/pubmed/18093943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710370104 |
Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|