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Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks
The caps on the ends of chromosomes, called telomeres, keep the ends of chromosomes from appearing as DNA double-strand breaks (DSBs) and prevent chromosome fusion. However, subtelomeric regions are sensitive to DSBs, which in normal cells is responsible for ionizing radiation-induced cell senescenc...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652756/ https://ncbi.nlm.nih.gov/pubmed/26209132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv714 |
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