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Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks

The caps on the ends of chromosomes, called telomeres, keep the ends of chromosomes from appearing as DNA double-strand breaks (DSBs) and prevent chromosome fusion. However, subtelomeric regions are sensitive to DSBs, which in normal cells is responsible for ionizing radiation-induced cell senescenc...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Muraki, Keiko, Han, Limei, Miller, Douglas, Murnane, John P.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652756/
https://ncbi.nlm.nih.gov/pubmed/26209132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv714
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