Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation

High-linear energy transfer ionizing radiation, derived from high charge (Z) and energy (E) (HZE) particles, induces clustered/complex DNA double-strand breaks (DSBs) that include small DNA fragments, which are not repaired by the non-homologous end-joining (NHEJ) pathway. The homologous recombinati...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Xie, Maohua, Park, Dongkyoo, You, Shuo, Li, Rui, Owonikoko, Taofeek K., Wang, Ya, Doetsch, Paul W., Deng, Xingming
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333404/
https://ncbi.nlm.nih.gov/pubmed/25567982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1358
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