The progesterone antagonist RU486 acquires agonist activity upon stimulation of cAMP signaling pathways.

The protein kinase A stimulator cAMP can potentiate the ability of progestins to induce the transactivation function of the human progesterone receptor (hPR). We questioned in the present study whether cAMP could functionally cooperate with the progestin antagonist RU486. In T47D human breast cancer...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Beck, C A, Weigel, N L, Moyer, M L, Nordeen, S K, Edwards, D P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46527/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4441
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!