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Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse

BACKGROUND: Use of low doses of digitalis to prevent the development of heart failure was advocated decades ago, but conflicting results of early animal studies dissuaded further research on this issue. Recent discoveries of digitalis effects on cell signal pathways prompted us to reexamine the poss...

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Bibliografiske detaljer
Udgivet i:Cell Biosci
Main Authors: Wu, Jian, Li, Daxiang, Du, Lingling, Baldawi, Mustafa, Gable, Marjorie E., Askari, Amir, Liu, Lijun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652409/
https://ncbi.nlm.nih.gov/pubmed/26587223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0053-7
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