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Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse

BACKGROUND: Use of low doses of digitalis to prevent the development of heart failure was advocated decades ago, but conflicting results of early animal studies dissuaded further research on this issue. Recent discoveries of digitalis effects on cell signal pathways prompted us to reexamine the poss...

詳細記述

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書誌詳細
出版年:Cell Biosci
主要な著者: Wu, Jian, Li, Daxiang, Du, Lingling, Baldawi, Mustafa, Gable, Marjorie E., Askari, Amir, Liu, Lijun
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652409/
https://ncbi.nlm.nih.gov/pubmed/26587223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0053-7
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