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Different roles of the cardiac Na(+)/Ca(2+)-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy
Previous studies have shown that digitalis drugs, acting as specific inhibitors of cardiac Na(+)/K(+)-ATPase, not only cause positive inotropic effects, but also activate cell signaling pathways that lead to cardiac myocyte hypertrophy. A major aim of this work was to assess the role of Na(+)/Ca(2+)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774505/ https://ncbi.nlm.nih.gov/pubmed/23203972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00462.2012 |
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