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Ligand-driven conformational changes of MurD visualized by paramagnetic NMR

Proteins, especially multi-domain proteins, often undergo drastic conformational changes upon binding to ligands or by post-translational modifications, which is a key step to regulate their function. However, the detailed mechanisms of such dynamic regulation of the functional processes are poorly...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Saio, Tomohide, Ogura, Kenji, Kumeta, Hiroyuki, Kobashigawa, Yoshihiro, Shimizu, Kazumi, Yokochi, Masashi, Kodama, Kota, Yamaguchi, Hiroto, Tsujishita, Hideki, Inagaki, Fuyuhiko
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652230/
https://ncbi.nlm.nih.gov/pubmed/26582338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16685
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