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Microgravity Reduces the Differentiation and Regenerative Potential of Embryonic Stem Cells

Mechanical unloading in microgravity is thought to induce tissue degeneration by various mechanisms, including inhibition of regenerative stem cell differentiation. To address this hypothesis, we investigated the effects of microgravity on early lineage commitment of mouse embryonic stem cells (mESC...

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Foilsithe in:Stem Cells Dev
Main Authors: Blaber, Elizabeth A., Finkelstein, Hayley, Dvorochkin, Natalya, Sato, Kevin Y., Yousuf, Rukhsana, Burns, Brendan P., Globus, Ruth K., Almeida, Eduardo A.C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Mary Ann Liebert, Inc. 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652210/
https://ncbi.nlm.nih.gov/pubmed/26414276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0218
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