Microgravity Reduces the Differentiation and Regenerative Potential of Embryonic Stem Cells

Mechanical unloading in microgravity is thought to induce tissue degeneration by various mechanisms, including inhibition of regenerative stem cell differentiation. To address this hypothesis, we investigated the effects of microgravity on early lineage commitment of mouse embryonic stem cells (mESC...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Blaber, Elizabeth A., Finkelstein, Hayley, Dvorochkin, Natalya, Sato, Kevin Y., Yousuf, Rukhsana, Burns, Brendan P., Globus, Ruth K., Almeida, Eduardo A.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652210/
https://ncbi.nlm.nih.gov/pubmed/26414276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0218
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