Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem Cells

Background/Aims: Embryonic developmental studies under microgravity conditions in space are very limited. To study the effects of altered gravity on the embryonic development processes we established an in vitro methodology allowing differentiation of mouse embryonic stem cells (mESCs) under simulat...

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Main Authors: Vaibhav Shinde, Sonja Brungs, Margit Henry, Lucia Wegener, Harshal Nemade, Tamara Rotshteyn, Aviseka Acharya, Christa Baumstark-Khan, Christine E. Hellweg, Jürgen Hescheler, Ruth Hemmersbach, Agapios Sachinidis
Format: Artigo
Sprog:Inglês
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2016-04-01
Serier:Cellular Physiology and Biochemistry
Fag:
Embryonic stem cells
Differentiation
Transcriptomics
Signal transduction pathways
Clinostat
Cardiomyogenesis
Microgravity
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