Microgravity Induces Pelvic Bone Loss through Osteoclastic Activity, Osteocytic Osteolysis, and Osteoblastic Cell Cycle Inhibition by CDKN1a/p21

Bone is a dynamically remodeled tissue that requires gravity-mediated mechanical stimulation for maintenance of mineral content and structure. Homeostasis in bone occurs through a balance in the activities and signaling of osteoclasts, osteoblasts, and osteocytes, as well as proliferation and differ...

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Detalhes bibliográficos
Main Authors: Blaber, Elizabeth A., Dvorochkin, Natalya, Lee, Chialing, Alwood, Joshua S., Yousuf, Rukhsana, Pianetta, Piero, Globus, Ruth K., Burns, Brendan P., Almeida, Eduardo A. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630201/
https://ncbi.nlm.nih.gov/pubmed/23637819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061372
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