PKC-α-dependent augmentation of cAMP and CREB phosphorylation mediates the angiotensin II stimulation of renin in the collecting duct

In contrast to the negative feedback of angiotensin II (ANG II) on juxtaglomerular renin, ANG II stimulates renin in the principal cells of the collecting duct (CD) in rats and mice via ANG II type 1 (AT(1)R) receptor, independently of blood pressure. In vitro data indicate that CD renin is augmente...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Renal Physiol
Päätekijät: Gonzalez, Alexis A., Liu, Liu, Lara, Lucienne S., Bourgeois, Camille R. T., Ibaceta-Gonzalez, Cristobal, Salinas-Parra, Nicolas, Gogulamudi, Venkateswara R., Seth, Dale M., Prieto, Minolfa C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2015
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652074/
https://ncbi.nlm.nih.gov/pubmed/26268270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00155.2015
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