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PKC-α-dependent augmentation of cAMP and CREB phosphorylation mediates the angiotensin II stimulation of renin in the collecting duct
In contrast to the negative feedback of angiotensin II (ANG II) on juxtaglomerular renin, ANG II stimulates renin in the principal cells of the collecting duct (CD) in rats and mice via ANG II type 1 (AT(1)R) receptor, independently of blood pressure. In vitro data indicate that CD renin is augmente...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652074/ https://ncbi.nlm.nih.gov/pubmed/26268270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00155.2015 |
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