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PGE(2) upregulates renin through E-prostanoid receptor 1 via PKC/cAMP/CREB pathway in M-1 cells

During the early phase of ANG II-dependent hypertension, tubular PGE(2) is increased. Renin synthesis and secretion in the collecting duct (CD) are upregulated by ANG II, contributing to further intratubular ANG II formation. However, what happens first and whether the triggering mechanism is indepe...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Physiol Renal Physiol
Main Authors: Gonzalez, Alexis A., Salinas-Parra, Nicolas, Leach, Dan, Navar, L. Gabriel, Prieto, Minolfa C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668586/
https://ncbi.nlm.nih.gov/pubmed/28701311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00194.2017
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