SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer

A number of tumors exhibit an altered expression of sirtuins, including NAD(+)-dependent histone deacetylase silent information regulator 1 (SIRT1) that may act as a tumor suppressor or tumor promoter mainly depending on the tumor types. For instance, in breast cancer cells SIRT1 was shown to exert...

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Publicat a:Cell Death Dis
Autors principals: Santolla, M F, Avino, S, Pellegrino, M, De Francesco, E M, De Marco, P, Lappano, R, Vivacqua, A, Cirillo, F, Rigiracciolo, D C, Scarpelli, A, Abonante, S, Maggiolini, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650744/
https://ncbi.nlm.nih.gov/pubmed/26225773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.201
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